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Academic Report: Rapid 3D BioPrinting: An Enabling Platform for Precision Tissue Engineering


主题:Rapid 3D BioPrinting: An Enabling Platform for Precision Tissue Engineering

报告人:Shaochen Chen


地点:玉泉校区 图书馆二楼报告厅



In this talk, he will present our laboratory’s recent research efforts in rapid 3D bioprinting to create 3D scaffolds and tissue constructs using a variety of biomaterials. These 3D biomaterials are functionalized with precise control of micro-architecture, mechanical (e.g. stiffness), chemical, and biological properties. Design, fabrication, and experimental results will be discussed. Such functional biomaterials allow us to investigate cell-microenvironment interactions at nano- and micro-scales in response to integrated physical and chemical stimuli. From these fundamental studies we can create both in vitro and in vivo microphysiological systems such as nerve conduits for spinal cord repair [1] and a human liver tissue for disease modeling and drug discovery [2]. To vascularize these engineered tissues, we have also developed a prevascularization technique by using the rapid 3D bioprinting method [3]. Multiple cell types mimicking the native vascular cell composition were encapsulated directly into hydrogels with precisely controlled distribution.

Short Bio:

Dr. Shaochen Chen is a Professor and Vice Chair in the NanoEngineering Department and Professor in the Bioengineering Department at the University of California, San Diego (UCSD). He is the founding co-director of the Biomaterials and Tissue Engineering Center at UCSD. Before joining UCSD, Dr. Chen had been a Professor and a Henderson Centennial Endowed Faculty Fellow in Engineering at the University of Texas at Austin from 2001 to 2010. Between 2008 and 2010, he served as the Program Director for the Nanomanufacturing Program of the National Science Foundation (NSF). Dr. Chen’s primary research interests include: 3D printing and bioprinting, biomaterials and nanomaterials, stem cell and regenerative medicine, tissue engineering. He has published over 140 papers in top journals and 17 book/book chapters. Among his numerous awards, Dr. Chen received the NSF CAREER award, ONR Young Investigator award, and NIH Edward Nagy New Investigator Award. In 2017, He received the Milton C. Shaw Manufacturing Research Medal from ASME for his seminal work in 3D printing, bioprinting, and nanomanufacturing. Dr. Chen is a Fellow of AAAS, AIMBE, ASME, SPIE, and ISNM.

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